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Histamine binds to receptors (docking stations) on specific cells, which trigger several responses such as dilation of the blood vessels, which causes fluid to leak into nearby tissue (runny nose, watery eyes for example) as well as inducing itchiness and smooth muscle contraction, which can lead to breathing difficulty due to bronchodilation.Antihistamines work by competing with histamine to bind to the receptors on the cells.~ Karen Siouxsie: We certainly don’t blame poor Graylie for being traumatized by that! Thomas: One of the reasons why cats get to the vet so much less often than dogs is because so many cats don’t like carrier rides and lead their people on a merry chase, which often ends up with the cat disappearing and the person having to call the vet and cancel the appointment.Bella: House-call vets can be a godsend for people whose cats freak out at the vet, and that may be a good option for your Graylie.I’ve bought “calming” stuff at the pet store — various kinds, expensive stuff — and I don’t see that it helps. I’ve been told by a vet that sedating him is a bad idea. He is past his time for his rabies protection now; fortunately, he is an indoor cat, but I’m out of compliance with state law.Is there any way I can calm him at home long enough to get him into a carrier?Thomas: There are some great videos available on how to handle and restrain fractious cats. Sophia Yin (1966-2014) shared this video of correctly restraining a feral cat for an examination.Bella: In this 10-minute training video from Dove Lewis Animal Emergency Hospital in Portland, Oregon, a pair of vet nurses demonstrate safe restraint techniques for a very fractious cat who has been “fired” from two other clinics because of his aggressiveness: Siouxsie: So, Karen, you can see that vet clinic staff trained in safe, low-stress restraint techniques can keep even a freaked out cat from getting hurt or hurting the people trying to treat him.

What techniques have you used to get your cat to love the carrier?Intradermal allergy testing: This may be necessary for other types of allergy to determine the cause.An area of skin on the belly is shaved, several allergens are then injected into the skin.If your cat has an allergy to a specific allergen, small red hives will appear.Your veterinarian may recommend a trial, to determine the most effective antihistamine for your cat.

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This can vary depending on the underlying cause, but it is common for allergies in cats to affect the skin.

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