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All genotypes appear to have the same risk of transmission.
HCV infection is frequently found in children who have previously been presumed to have non-A, non-B hepatitis and cryptogenic liver disease.
This is particularly true in those with human immunodeficiency virus infection, recipients of organ transplants, and those with hypogammaglobulinemia.
Higher rates have been reported for both vertical transmission (18%, 6–36% and 41%). Breastfeeding is considered safe if the nipples are not damaged.
Infection around the time of birth in one child does not increase the risk in a subsequent pregnancy.
Despite this discovery, international research efforts to identify the virus, initially called non-A, non-B hepatitis (NANBH), failed for the next decade.
In 1987, Michael Houghton, Qui-Lim Choo, and George Kuo at Chiron Corporation, collaborating with Daniel W.
One barrier to finding treatments for hepatitis C is the lack of a suitable animal model.